MTI-101 treatment inducing activation of Stim1 and TRPC1 expression is a determinant of response in multiple myeloma

Abstract The emergence of drug resistance continues to be a major Canes hurdle towards improving patient outcomes for the treatment of Multiple Myeloma.MTI-101 is a first-in-class peptidomimetic that binds a CD44/ITGA4 containing complex and triggers necrotic cell death in multiple myeloma cell lines.In this report, we show that acquisition of resi

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Cortical control of a tablet computer by people with paralysis.

General-purpose computers have become ubiquitous and Baby Oil important for everyday life, but they are difficult for people with paralysis to use.Specialized software and personalized input devices can improve access, but often provide only limited functionality.In this study, three research participants with tetraplegia who had multielectrode arr

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From the Patrimonial to the Civic Standard of Music for All: The Transformations of Musical Institutions in Nineteenth-Century Bohemia and the Problems of Their Music-Historical Interpretation

The topic of institutionalisation of musical life in the nineteenth century invites a new perspective on the transformation processes in multinational Austria.The Kingdom of Bohemia is an example of a bilingual country in which the development of civil institutions together latigos with a national movement was quite successful.These processes took

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